Gastrin is secreted from which type of cells in the stomach?

Gastrin is a hormone that is secreted by G cells, which are a type of endocrine cell found in the gastric mucosa of the stomach. These G cells play a crucial role in the digestive process by stimulating the secretion of gastric acid (HCl) from parietal cells in the stomach, thereby aiding in digestion and managing the pH of the stomach contents. The action of gastrin is part of a feedback mechanism that regulates food digestion.

Endocrine cells, like the G cells, release hormones directly into the bloodstream, allowing gastrin to circulate and exert its effects at different sites in the stomach. This contrasts with other cell types in the stomach—such as parietal cells that secrete hydrochloric acid, exocrine cells that produce digestive enzymes and mucus, and goblet cells that secrete mucus specifically for lubrication and protection. The specific role of the G cells in releasing gastrin emphasizes their importance in the hormonal regulation of gastric function.