What does CCK help to control in relation to the ileocecal sphincter?

Cholecystokinin (CCK) plays a significant role in the digestive process, particularly in regulating the function of the ileocecal sphincter, which is located between the small intestine (ileum) and the large intestine (cecum). CCK is released when fatty acids and amino acids enter the duodenum, leading to multiple digestive effects.

One of its primary functions is to inhibit the contraction of the ileocecal sphincter. This inhibition allows for the passage of the contents from the ileum into the cecum. By relaxing the sphincter, CCK facilitates the movement of digested food into the large intestine for further processing. This regulatory mechanism is essential for maintaining a smooth flow of digestion and preventing the backup of intestinal contents.

In summary, CCK's inhibitory effect on the contraction of the ileocecal sphincter is crucial for regulating gastrointestinal motility and ensuring the proper progression of food through the digestive tract.