What might be a physical manifestation of esophageal cancer in a patient?

In the case of esophageal cancer, one of the most common physical manifestations is weight loss. This occurs for several reasons related to the disease and its effects on the body. As the cancer progresses, it may cause difficulty swallowing (dysphagia), which leads to a decreased ability or willingness to eat. Patients may also experience pain or discomfort while eating, which can further diminish their food intake and result in unintentional weight loss. Additionally, esophageal cancer can lead to metabolic changes and increased energy expenditure, contributing to weight reduction.

The other choices, such as excessive weight gain or an enhanced appetite, are typically not associated with esophageal cancer. Instead, the disease often leads to opposite effects in terms of nutritional intake and weight status, making weight loss a significant and observable symptom in affected individuals. Susceptibility to infections may be relevant in later stages of disease or treatment phases, but it is not a direct manifestation of esophageal cancer itself.