Which hormone is known for its role in inhibiting gastric motility?

The hormone that plays a significant role in inhibiting gastric motility is gastric inhibitory peptide (GIP). GIP is released from the K cells in the duodenum in response to the presence of fatty acids and glucose in the intestinal lumen. Its primary functions include slowing the gastric emptying process and promoting insulin secretion from the pancreas in order to manage blood glucose levels.

By inhibiting gastric motility, GIP helps to coordinate digestion and absorption processes, allowing sufficient time for nutrients to be processed in the small intestine rather than overwhelming it with rapid gastric contents. This regulation is crucial for effective nutrient absorption and for maintaining proper digestive function.

Other hormones involved in digestive processes, such as glucagon, gastrin, and cholecystokinin, have different roles. Glucagon primarily functions in raising blood glucose levels. Gastrin stimulates gastric acid secretion and promotes gastric motility, while cholecystokinin encourages the release of digestive enzymes from the pancreas and bile from the gallbladder, also typically facilitating motility rather than inhibiting it. Thus, gastric inhibitory peptide is distinct in its function, making it the correct choice in the context of inhibiting gastric motility.