Which two amino acids are known to stimulate vagal stimulation and gastrin release?

The amino acids that stimulate vagal stimulation and gastrin release include tryptophan and phenylalanine. This is significant in the context of digestive physiology, as gastrin plays a crucial role in regulating gastric acid secretion and promoting gastric motility.

Tryptophan is known for its role as a precursor to serotonin, influencing gut motility and possibly contributing to the signaling pathways that stimulate the vagus nerve. Phenylalanine, on the other hand, is also involved in neurotransmitter synthesis, which can affect various physiological responses, including those related to digestion.

The interaction between these amino acids and the release of hormones such as gastrin demonstrates the complex network of nutrient signaling that helps regulate digestive functions. The stimulation of vagal pathways by these amino acids emphasizes the connection between diet, the nervous system, and gastrointestinal activities.